Poloxafuse-I™ is a formulation under development that is designed to address cell injury for instances of general trauma where a common pathology is damage to the cell membrane. These include, but are not limited to, burn, electrical, radiological, and other chemical, biochemical, and physical injuries. Poloxafuse-I™ comprises a synthetic, biocompatible surfactant copolymer that is capable of sealing porated cell membranes and other compounds that provide specific benefits to the condition being treated. These other compounds may include free radical scavengers, cofactors to stabilize cell function, commercially available pharmaceuticals, and others.